Table 1 Hematology, serum chemistry, C-reactive protein, plasma Immunoglobulin E in weeks 4, 8 and 12 in dogs fed control and experimental diets.

From: Unraveling the role of shrimp hydrolysate as a food supplement in the immune function and fecal microbiota of beagle dogs

Item

Week 4

Week 8

Week 12

SEM2

P - value

Control1

Experimental1

Control1

Experimental1

Control1

Experimental1

Diet

Week

Diet*Week

White blood cells, × 103/µL

6.86

7.09

6.83

7.62

6.45

8.29

0.433

0.002

0.601

0.139

Neutrophils, %

54.7

54.7

50.8

56.2

54.2

59.3

1.93

0.036

0.129

0.168

Lymphocytes, %

35.0

35.8

37.2

32.7

34.9

30.7

2.05

0.183

0.265

0.219

Monocytes, %

5.54

4.91

5.42

5.21

5.79

5.81

0.467

0.437

0.347

0.734

Eosinophils, %

4.80

4.25

6.63

5.50

5.11

3.75

0.500

0.017

0.003

0.671

Red blood cells, × 106/µL

7.10a

7.30a, b,c

7.43b, c,d

7.38a, b,c

7.49c, d

7.18a, b

0.153

0.636

0.068

0.044

Hemoglobin, g/dL

16.6a

17.1a, b,c

17.6b, c

17.4b, c

17.7c

16.9a, b

0.37

0.596

0.013

0.037

Platelets, × 103/µL

301

318

252

294

270

289

17.0

0.038

0.040

0.632

Mean platelet volume, fL

10.1

10.1

9.87

9.88

9.64

9.76

0.192

0.914

0.004

0.650

Total protein, g/dL

5.51

5.61

5.85

6.07

5.78

5.89

0.098

0.106

0.001

0.740

Albumin, g/dL

3.59

3.64

3.81

3.89

3.83

3.82

0.061

0.565

< 0.001

0.657

Globulin, g/dL

1.93

1.97

2.04

2.18

1.95

2.06

0.062

0.067

0.054

0.720

Glucose, mg/dL

87.2

82.6

101

95.3

90.3

81.4

2.60

0.023

< 0.001

0.608

Creatinine, mg/dL

0.764

0.836

0.880

0.793

0.762

0.808

0.0635

0.894

0.456

0.143

Urea, mg/dL

26.5

28.7

38.0

28.0

34.5

28.9

3.55

0.098

0.229

0.172

Alanine aminotransferase, U/L

27.7

36.6

27.2

29.4

30.4

29.3

3.34

0.218

0.471

0.273

Alkaline phosphatase, U/L

43.5

45.7

43.3

45.8

42.3

44.0

2.16

0.396

0.618

0.966

C-reactive protein, µg/mL

7.37

8.23

8.41

9.09

5.19

9.01

1.054

1.22

0.234

0.318

Immunoglobulin E, µg/mL

216

195

241

177

55.9

71.3

26.1

0.438

< 0.001

0.135

  1. 1Control: complete diet without the inclusion of shrimp hydrolysate; Experimental: control diet with 5% of shrimp hydrolysate in replacement of wheat gluten.
  2. 2SEM: Standard error of the mean.
  3. a, b,c, dMeans with different superscript letters in the same row are significantly different (P < 0.05).