Table 3 Concentration of cytokines after lymphocyte stimulation with Concanavalin A in weeks 4, 8 and 12 of dogs fed the control and experimental diets.

From: Unraveling the role of shrimp hydrolysate as a food supplement in the immune function and fecal microbiota of beagle dogs

Item

Week 4

Week 8

Week 12

SEM2

P - value

Control1

Experimental1

Control1

Experimental1

Control1

Experimental1

Diet

Week

Diet*Week

IL-17, pg/mL

470

334

1284

1202

2177

1422

509.3

0.405

0.027

0.752

IFN-γ, pg/mL

2762

1626

1586

1883

1308

875

471.1

0.452

0.011

0.122

TNF-α, pg/mL

25.2

29.4

18.6

19.7

47.8

35.3

5.90

0.594

0.004

0.317

IL-10, pg/mL

135

72.7

156

148

289

211

44.27

0.124

0.002

0.729

  1. 1Control: complete diet without the inclusion of shrimp hydrolysate; Experimental: control diet with 5% of shrimp hydrolysate in replacement of wheat gluten.
  2. 2SEM: Standard error of the mean.
  3. Abbreviations: IFN-γ: interferon-gamma; IL, interleukin; TNF-α: tumor necrosis factor alpha.
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