Fig. 11 | Scientific Reports

Fig. 11

From: Exploring the anti-inflammatory mechanism of geniposide in rheumatoid arthritis via network pharmacology and experimental validation

Fig. 11

GE attenuated the severity of arthritis in CIA mice. (A) In vivo experiment flow chart. (B) Observation of foot paw swelling in CIA model mice induced by GE. (C) Effects of GE on body weight and hind paw swelling of CIA model mice. (D) ELISA was used to detect the effect of GE on the inflammation of CIA model mice. (E) HE staining results of CIA mice joints after GE treatment. Black arrows indicate cartilage destruction, and asterisks indicate inflammatory cell infiltration. Compared with Control group, ####P < 0.0001. Compared with CIA group, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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