Fig. 8

Effect of different concentrations of GE on inflammatory cytokine release in RA-FLS cells. After 24 h of GE treatment, the expression level of inflammatory factors in the supernatant of RA-FLS cells was determined by ELISA assay. (A) IL-8. (B) IL-17. (C) TNF-α. (D) MMP-3. (E) MMP-9. Compared with the blank control group, ###P < 0.001. Compared with the TNF-α stimulus group, **P < 0.01, ****P < 0.0001.