Fig. 3
From: Identification of potential shared core biomarkers in type 2 diabetes and sarcopenia
Visualization of the PPI network of candidate genes and identification of hub genes. (A) Interaction network illustrating the relationships among 30 candidate genes. Each node represents a protein labeled with its corresponding gene name. Red nodes indicate proteins upregulated in both T2D and SA, whereas blue nodes represent those consistently downregulated across the two conditions. (B) Venn diagram comparing the top 50 hub genes identified by four distinct topological algorithms: MCC, MNC, DEGREE, and EPC. The overlapping regions highlight genes concurrently selected by multiple algorithms, each represented by a specific color. T2D, type 2 diabetes; SA, sarcopenia; MCC, maximal clique centrality; MNC, maximum neighborhood component; EPC, edge percolated component.
