Fig. 6

Relative gene expression of (A) COX-1 and (B) COX-2. The cells were treated with different concentrations of C. fragrans extracts (25 and 200 µg/mL of control and polyploid extract) with H2O2 (25 µM) for 24 h. The treated groups are compared to the control (CTRL+) and H2O2. The data are presented as mean ± SEM from at least three independent experiments. H + C25/200 = H2O2 + C. fragrans control diploid extract. H + P25/200 = H2O2 + C. fragrans polyploid extract. *** (P < 0.001), ** (P < 0.01) and * (P < 0.05) vs. CTRL+. ### (P < 0.001), ## (P < 0.01) and # (P < 0.05) vs. H2O2. The picture of gel is presented in Supplementary Figure S3.