Fig. 5
Restoration of pRb function in ABE-treated R552X cell lines. (A) Representative images of western blot analysis of pRb expression in ABE-treated R552X cell lines. (B) Protein expression level of pRb measured by western blot analysis (n = 4; mean ± s.e.m.). The average expression level of WT cells was normalized to 1, and the expression levels of the other cell lines were adjusted accordingly. (C) Relative cell proliferation rate. Cell expansion rate of each cell line was calculated using 6 independent measurements (n = 6; mean ± SEM) up to day 3. P values were obtained using one-way analysis of variance (ANOVA) and Tukey’s test for post hoc analysis: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
