Fig. 6 | Scientific Reports

Fig. 6

From: M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway

Fig. 6

TGF-β1 derived from M2-like macrophages triggers HSFs differentiation into myofibroblast is associated with the SMAD2/3 signaling pathway. Expression of the TGF‑β pathway in HSF cells was assessed by western blot analysis. (A and B) Representative western blot images and results of statistical analysis of protein levels (A) and phosphorylation levels (B) of SMAD2/3 following the indicated treatment. Data are presented as the mean ± SEM from three independent experiments. *p < 0.05, **p < 0.01.

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