Fig. 6
From: A new class of human CpG Island promoters with primate-specific repeats
Evolutionary origins of TRs in TR-CGI genes. (A) For each orthologous gene, dot plots of the CGI-promoters and surrounding sequences from the five species are displayed. Blue rectangles are TR-CGIs and black rectangles are CGIs without TRs. Arrows are transcriptional start sites and directions of transcription. (B) Comparisons of methylation profiles of orthologous genes in human, Rhesus macaque and mouse. *** indicates p values < 0.0001 estimated by Fisher’s paired t-test. *TR present in human, but not in Rhesus macaque or mouse. +TR present in mouse, but not in human or Rhesus macaque. The results were obtained after analysis of publicly available datasets: GSE124708, GSE110366, GSE233417, GSE120137.
