Table 1 The baseline characteristics of participants.

From: A non-linear association between AST/ALT ratio and 28-day mortality in critically ill elderly: evidence from a multicenter study

Variables

AST/ALT ratio

P value

Tertile 1

(0.075–1.043)

n = 7452

Tertile 2

(1.043–1.582)

n = 7441

Tertile 3

(1.583–4.687)

n = 7468

Demographics

 Male (%)

3387 (45.46%)

3600 (48.39%)

3727 (49.93%)

< 0.001

 Age (years)

75.62 ± 7.27

76.70 ± 7.53

76.76 ± 7.55

< 0.001

 Ethnicity

< 0.001

 Caucasian (%)

6155 (82.60%)

6000 (80.63%)

5975 (80.01%)

 

 Other (%)

1297 (17.41%)

1441 (19.37%)

1493 (19.99%)

 

 BMI (kg/m2)

28.61 ± 6.99

27.92 ± 6.81

27.47 ± 6.78

< 0.001

Comorbidities

 Pneumonia (%)

1217 (16.33%)

1150 (15.46%)

1151 (15.41%)

0.220

 AMI (%)

252 (3.38%)

340 (4.60%)

718 (9.61%)

< 0.001

 Arrhythmias (%)

1668 (22.38%)

1683 (22.62%)

1587 (21.25%)

0.099

 CHF (%)

1009 (13.54%)

942 (12.66%)

858 (11.49%)

< 0.001

 DM (%)

982 (13.18%)

862 (11.58%)

801 (10.73%)

< 0.001

Scoring systems

 Acute physiology score III

46.54 ± 19.78

49.48 ± 20.95

52.83 ± 22.18

< 0.001

 GCS score

13.04 ± 3.18

12.63 ± 3.52

12.25 ± 3.77

< 0.001

 Apache IV score

64.13 ± 20.45

67.60 ± 21.45

71.00 ± 22.75

< 0.001

Vital signs

 Temperature (°C)

36.42 ± 0.56

36.39 ± 0.63

36.36 ± 0.69

< 0.001

 Respiratory rate (bpm)

26.22 ± 14.62

26.99 ± 14.83

27.25 ± 15.03

< 0.001

 Heart rate (bpm)

98.87 ± 32.26

100.26 ± 32.01

102.44 ± 31.33

< 0.001

 MAP (mmHg)

87.42 ± 43.68

84.64 ± 44.10

82.33 ± 44.64

< 0.001

Laboratory data

 Glucose (mg/dL)

145.99 ± 57.39

144.72 ± 56.96

141.46 ± 55.17

< 0.001

 BUN (mg/dL)

29.02 ± 17.67

28.89 ± 17.39

30.13 ± 18.30

< 0.001

 Creatinine (mg/dL)

1.40 ± 1.00

1.49 ± 1.04

1.63 ± 1.13

< 0.001

 Albumin (g/dL)

2.86 ± 0.60

2.86 ± 0.64

2.80 ± 0.67

< 0.001

 PLT (k/mcl)

201.83 ± 84.04

196.16 ± 82.60

189.14 ± 86.70

< 0.001

 RBC (k/mcl)

3.69 ± 0.75

3.64 ± 0.72

3.57 ± 0.72

< 0.001

 WBC (cells × 109/L)

11.49 ± 5.99

11.90 ± 6.20

12.75 ± 6.78

< 0.001

 Hemoglobin (g/dL)

10.97 ± 2.26

10.82 ± 2.17

10.62 ± 2.17

< 0.001

 AST (U/L)

44.89 ± 85.36

67.01 ± 156.24

102.80 ± 219.36

< 0.001

 ALT (U/L)

60.97 ± 109.11

52.31 ± 120.63

45.37 ± 102.37

< 0.001

  1. Among the 22,361 patients, the amount of missing values for the covariates were 5 (0.02%) for gender, 667 (2.98%) for BMI, 3285 (14.69%) for Acute Physiology Score III, 3290 (14.71%) for Apache IV score, 851 (3.81%) for GCS, 2289 (10.24%) for temperature, 640 (2.86%) for respiratory rate, 572 (2.56%) for MAP, 560 (2.50%) for heart rate, 516 (2.31%) for glucose, 875 (3.91%) for BUN, 606 (2.71%) for creatinine, 240 (1.07%) for albumin, 1056 (4.72%) for PLT, 832 (3.72%) for RBC, 988 (4.42%) for WBC, 632 (2.83%) for hemoglobin.
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