Table 2 The univariate logistic analysis between factors and 28-day mortality.

From: A non-linear association between AST/ALT ratio and 28-day mortality in critically ill elderly: evidence from a multicenter study

Exposure

Statistics

HR (95% CI)

P value

Demographics

 Male

10,714 (47.92%)

Ref

0.206

 Female

11,642 (52.08%)

0.941 (0.855, 1.034)

 Age

76.36 ± 7.47

1.018 (1.012, 1.025)

< 0.001

 Ethnicity

  Caucasian

18,130 (81.08%)

1.154 (1.02, 1.31)

0.025

  Other

4231 (18.92%)

Ref

 BMI (kg/m2)

28.00 ± 6.87

0.986 (0.979, 0.993)

< 0.001

Comorbidities

 Pneumonia

  No

18,843 (84.27%)

Ref

0.053

  Yes

3518 (15.73%)

1.116 (0.998, 1.247)

 AMI

  No

21,051 (94.14%)

Ref

< 0.001

  Yes

1310 (5.86%)

1.341 (1.130, 1.592)

 Arrhythmias

  No

17,423 (77.92%)

Ref

< 0.001

  Yes

4938 (22.08%)

1.290 (1.165, 1.429)

 CHF

  No

19,552 (87.44%)

Ref

0.760

  Yes

2809 (12.56%)

1.021 (0.893, 1.168)

 DM

  No

19,716 (88.17%)

Ref

0.502

  Yes

2645 (11.83%)

0.952 (0.826, 1.098)

Scoring systems

 Acute Physiology Score III

49.62 ± 21.15

1.026 (1.024, 1.029)

< 0.001

 GCS score

12.64 ± 3.52

0.896 (0.886, 0.906)

< 0.001

 Apache IV score

67.59 ± 21.75

1.026 (1.024, 1.029)

< 0.001

Vital signs

 Temperature (°C)

36.39 ± 0.63

0.678 (0.632, 0.728)

< 0.001

 Respiratory rate (bpm)

26.82 ± 14.83

1.012 (1.009, 1.016)

< 0.001

 Heart rate (bpm)

100.53 ± 31.90

1.007 (1.005, 1.008)

< 0.001

 MAP (mmHg)

84.79 ± 44.19

0.998 (0.997, 0.999)

0.003

Laboratory data

 Glucose (mg/dL)

144.06 ± 56.54

1.003 (1.002, 1.004)

< 0.001

 BUN (mg/dL)

29.35 ± 17.80

1.012 (1.010, 1.014)

< 0.001

 Creatinine (mg/dL)

1.51 ± 1.06

1.210 (1.168, 1.254)

< 0.001

 Albumin (g/dL)

2.84 ± 0.64

0.684 (0.635, 0.736)

< 0.001

 PLT (k/mcl)

195.69 ± 84.62

0.999 (0.999, 1.000)

0.003

 RBC (k/mcl)

3.63 ± 0.73

1.005 (0.942, 1.073)

0.871

 WBC (cells × 109/L)

12.05 ± 6.35

1.033 (1.027, 1.040)

< 0.001

 Hemoglobin (g/dL)

10.80 ± 2.20

0.999 (0.978, 1.021)

0.918

 AST (U/L)

71.59 ± 164.89

1.001 (1.001, 1.001)

< 0.001

 ALT (U/L)

52.88 ± 111.13

1.002 (1.002, 1.002)

< 0.001

 AST/ALT

1.45 ± 0.76

1.406 (1.335, 1.481)

< 0.001

  1. HR hazard ratios, CI confidence interval.