Table 3 Association of AST/ALT ratio with 28-day all-cause mortality post-ICU admission in different models.

From: A non-linear association between AST/ALT ratio and 28-day mortality in critically ill elderly: evidence from a multicenter study

Exposure

Model 1

Model 2

Model 3

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

AST/ALT

1.406 (1.335, 1.481)

< 0.0001

1.410 (1.338, 1.486)

< 0.0001

1.263 (1.189, 1.342)

< 0.0001

AST/ALT tertile

 Low

Ref

Ref

Ref

 Middle

1.337 (1.171, 1.528)

< 0.0001

1.320 (1.155, 1.508)

< 0.0001

1.231 (1.066, 1.422)

0.0046

 High

1.962 (1.735, 2.218)

< 0.0001

1.942 (1.717, 2.197)

< 0.0001

1.544 (1.348, 1.768)

< 0.0001

 P for trend

1.409 (1.327, 1.497)

< 0.0001

1.404 (1.321, 1.491)

< 0.0001

1.244 (1.164, 1.330)

< 0.0001

  1. Model 1: We did not adjust for model variables. Model 2: include adjustments for age, gender, and ethnicity. Model 3: include adjustments for age, gender, ethnicity, respiratory rate, heart rate, MAP, AMI, pneumonia, GCS score, creatinine, albumin, WBC, hemoglobin.
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