Table 4 Threshold effect analysis of the AST/ALT ratio and 28-day all-cause mortality.

From: A non-linear association between AST/ALT ratio and 28-day mortality in critically ill elderly: evidence from a multicenter study

Models

Per-unit increase

Per-SD increase

HR (95% CI)

P value

HR (95% CI)

P value

Model I

One line effect

1.263 (1.189, 1.342)

< 0.0001

1.196 (1.141, 1.252)

 < 0.0001

Model II

 Turning point (K)

2.161

0.925

 AST/ALT ratio < K

1.439 (1.283, 1.614)

< 0.0001

1.321 (1.210, 1.442)

< 0.0001

 AST/ALT ratio > K

1.078 (0.941, 1.235)

0.2787

1.059 (0.954, 1.175)

0.2791

 P value for LRT test*

 

0.0080

 

0.0080

  1. Data were presented as HR (95% CI) P value. Model I: linear analysis. Model II: non-linear analysis. Adjusted for all variables in Models 3. LRT for logarithm likelihood ratio test. A *P value below 0.05 indicates a significant distinction between Model II and Model I.
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