Fig. 2 | Scientific Reports

Fig. 2

From: A prognostic signature for hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer

Fig. 2

Identification and validation of the prognostic signature. (A) Hazard ratios (HR) and p-values from Cox proportional hazards analyses for all differentially expressed cell cycle-related genes; (B) Comparison of the expression of three prognostic-related genes between HR+/HER2 BC tumor samples and normal control samples in the TCGA dataset; (C) Kaplan-Meier (KM) OS curves for CDKN2C, BRINP1, and SYCP2 genes in the TCGA dataset; (D) RNA expression profile of three prognostic genes between two risk groups in the TCGA dataset; (E) KM OS curves for patients with high and low HBPS scores in the TCGA dataset; (F,G) KM OS curves for patients with high and low HBPS scores in the GSE96058 and METABRIC validation datasets.

Back to article page