Fig. 1
From: Efficient spectral data reduction for accurate iodine quantification in multi-energy CT

Outline of the methodology to reduce complexity of input dimensions through the linear combination of four channel inputs into two new spectra. The CRLB uses these two inputs (Φ1 (E), Φ2 (E)) based on weighting scheme and the weights (a, b, c) to estimate the noise in the projections for two basis materials, iodine and water. The contribution weights for the 80 kVp, low energy channel and 140 kVp, high energy channel have values of 1.