Fig. 3 | Scientific Reports

Fig. 3

From: Effects of a single application of hydrolyzed fish collagen on dermal protein expression and tissue architecture in human skin models

Fig. 3

Tissue viability, TEER measurement and IL-18 secretion in 3D EpiDerm models treated with S-HFC (a, b, c) and F-HFC (d, e, f) at different concentrations (47.00; 28.20; 23.50 µg/mL, corresponding to 0.1%, 0.06% and 0.05% w/v of HFC) for 60 ± 1 min, compared to negative controls (CTRL-, vehicle alone). Positive controls (CTRL+) were treated with 5% SDS, whereas 0.00 µgHyp/mL stands for F (cream without addition of HFC). Values are mean ± SD from at least 3 independent experiments performed in triplicate. The significant differences are indicated by symbols on bars (**** p ≤ 0.0001, *** p ≤ 0.001, **p ≤ 0.01 vs. CTRL-).

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