Fig. 3 | Scientific Reports

Fig. 3

From: In vitro and in silico neuroprotective evaluation of new biotransformation metabolites of (-)-α-bisabolol

Fig. 3

Neuroprotection of bisabolol and its metabolites against H2O2-induced neurotoxicity in SH-SY5Y cells. Results were represented as means ± standard deviations (SD), with n = 5. * Indicates a statistically significant difference compared to the cell viability of H2O2-treated cells at p < 0.001. Statistical significance was determined using one-way ANOVA followed by Dunnett’s post-hoc test in GraphPad Prism® 10. Metabolites 2 and 6 showed more potent neuroprotection than the parent compound and other metabolites.

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