Fig. 5 | Scientific Reports

Fig. 5

From: In vitro and in silico neuroprotective evaluation of new biotransformation metabolites of (-)-α-bisabolol

Fig. 5

Neuroprotection against Aβ1-42 induced-neurotoxicity in SH-SY5Y cells. ECG: Epigallocatechin-3-gallate was used as a positive control. Values were represented as means ± standard deviations (SD), n = 5. * Indicates a statistically significant difference compared to the cell viability of Aβ1-42 -treated cells at p < 0.001. Statistical significance was determined using one-way ANOVA followed by Dunnett’s post-hoc test in GraphPad Prism® 10. Metabolites 2 and 6 were more neuroprotective than α-bisabolol and other metabolites.

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