Fig. 3
From: An in vivo rat model for comparing selective blockade between sensory and motor nerve conduction
Stability of MEP and SSEP recordings over time and under different body temperatures. (a,b) Representative MEP waveforms and quantitative analysis showing stable amplitude and latency over a 60-minute period (n = 6). (c,d) Representative SSEP waveforms and quantification also confirm stable signals up to 60 min (n = 6). (e,f) MEP waveforms and quantitative results under hypothermia (34–36 °C), normothermia (36–38 °C), and hyperthermia (38–40 °C). Hypothermia and hyperthermia both significantly reduced MEP amplitude, and latency was prolonged under hypothermia (n = 6). (g) Non-linear regression analysis reveals a strong relationship between body temperature and MEP amplitude (R2 = 0.8385, P < 0.0001). (h,i) Similar temperature effects were observed in SSEP: amplitude decreased significantly under hypo- and hyperthermia, while only hypothermia slightly increased latency (n = 6). (j) Non-linear regression analysis confirms a significant relationship between body temperature and SSEP amplitude (R2 = 0.7352, P < 0.0001). Data are shown as mean ± SD. Statistical analysis: two-way ANOVA (b,d) and one-way ANOVA (f,i), and non-linear regression (g,j); statistical significance: ns = not significant, *P < 0.05, ****P < 0.0001.
