Fig. 11 | Scientific Reports

Fig. 11

From: Folate-based binuclear Mn(II) chelates with 2,2’-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells

Fig. 11

The inhibitory effect of the prepared chelates on the migration of HCT116 cells that was treated by their IC50 concentrations and compared to the untreated HCT116 cells (control group). (A–D) Images show changes in wound size after treatment with Chelate 1 and Chelate 2 for 48 h, as compared to control. (E) Bar chart illustrates the percentage of wound closure, data are represented as the mean ± SD of three independent experiments, **P < 0.01 means statistically significant from the control. The statistical significance of the results was evaluated using a one-way ANOVA, followed by Tukey’s multiple comparison test to determine specific group differences.

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