Table 5 ELISA for determination of relative protein expression (fold change/ control) in HCT116 cells treated with Chelates 1 and 2 (IC50).

From: Folate-based binuclear Mn(II) chelates with 2,2’-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells

Relative protein expression (fold change/control)

Protein

Chelate 1/HCT116

Chelate 2/HCT116

Cyclin E

0.36112

0.523401

Cyclin A

0.433156

0.6788

CDK2

0.486642

0.58820

Caspase-3

5.390271

4.1617

BCL-2

0.435022

0.474159

Bax

3.5079

3.068