Fig. 1

Analytical pipeline applied for conducting phenome-wide association studies (PheWAS) in the Nagahama Study. A total of 129 1H NMR-measured compounds in plasma samples from 302 participants of the Nagahama study that passed quality check (QC) were used. The covariates adjusted in the regressions were sex, age, fasting time, and lipid-lowering medication status. This analysis pipeline was built with R scripts in the Nextflow framework.