Fig. 6 | Scientific Reports

Fig. 6

From: Quantitative 1H-NMR spectroscopy identifies metabolites and lipoprotein subclasses associated with intermediate phenotypes of chronic diseases in the Japanese Nagahama Study

Fig. 6

Association analyses between obesity phenotypes in the Nagahama Study population and metabolites and lipoprotein (sub)classes. 1H NMR spectroscopy was used to derive quantitative data for small molecular weight metabolites and lipoprotein classes and subclasses which were tested for association with body mass index (BMI) (A) and visceral fat (B) in 302 subjects of the Nagahama Study population. The inner circle displays the -log10(p-value) of each association, and significant associations are shown in orange dots (–Log10(p-value) > 6.40) and lack of association in black dots. The outer circle represents the regression coefficient as beta values for NMR measured compounds associated positively (red dots) or negatively (blue dots) with BMI or visceral fat. Forest plots show the significant associations between lipoprotein (sub)classes and BMI and visceral fat (C). The nomenclature used for each lipoprotein (sub)class is given in Supplementary Table S3. Details of the statistics of associations between NMR-derived compounds and BMI and visceral fat are given in Supplementary Tables S4 and S5.

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