Fig. 7 | Scientific Reports

Fig. 7

From: Quantitative 1H-NMR spectroscopy identifies metabolites and lipoprotein subclasses associated with intermediate phenotypes of chronic diseases in the Japanese Nagahama Study

Fig. 7

Phenotypes associated with Apo-B100 in the VLDL and IDL classes and the LDL-4 subclass in the Nagahama Study. Plasma concentrations of Apo-B100 in VLDL class (A), IDL class (B), and LDL-4 subclass (C) were acquired following 1H NMR metabolomic profiling and tested for evidence of association with phenotypes characterized in a subset of subjects of the Nagahama Study population (n = 302). The threshold of statistical significance of association (p < 4.11 × 10–7) was determined following the Bonferroni correction. Symbols indicate positive (filled upward triangle) or inverse (filled downward triangle) associations between the metabolites and the phenotypes. Significant associations are labelled with phenotype names and shown by filled triangles. Abd. Cir, Abdominal Circumference; BFM, Body Fat Mass; BMI, Body mass index; DBP, Diastolic Blood Pressure; FIVC, Forced Inspiratory Vital Capacity; L-, Left; R-, Right. Details of the statistics of associations are given in Supplementary Table S5 and illustrated in Supplementary Figure S3.

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