Fig. 3 | Scientific Reports

Fig. 3

From: In silico and in vitro investigations reveal pan-PPAR agonist activity and anti-NAFLD efficacy of polydatin by modulating hepatic lipid-energy metabolism

Fig. 3

Effect of polydatin on lipotoxic damage in steatotic cells. (a) The oxidative stress (lipids peroxidation) levels in steatotic HepG2 cells versus Silymarin (30 µM)- and Polydatin (30 µM)-treated groups, (b) effects of Polydatin treatment on cell lysate ALT level. Values denote mean ± SD of three experiments done in triplicate. The Polydatin treated groups were compared to the steatotic control group, showing a statistically significant reduction in oxidative stress (p ≤ 0.05).

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