Table 1 Parental and children Characteristics.

From: Neurodevelopmental status of children aged 12 to 60 months conceived with artificial oocyte activation in a Cross-Sectional study

Variable

ICSI

ICSI-AOA

P-value

No.

81

76

 

Maternal characteristics

Age at delivery, median (IQR), y

35.0 (32.0–38.0)

36.0 (33.0–39.0)

0.14

Educational level (%)

High school dropout

2 (2.5)

0 (0)

0.50

High school graduate or vocational school graduate

29 (35.8)

26 (34.2)

0.87

College dropout

1 (1.2)

1 (1.3)

> 0.99

College graduate

43 (53.1)

43 (56.6)

0.87

Graduate school degree holder

3 (3.7)

6 (7.9)

0.32

Declined or unknown

3 (3.7)

0 (0)

0.25

Profession (%)

Healthcare worker

19 (23.5)

12 (15.8)

0.24

Office worker

14 (17.3)

22 (28.9)

0.09

Teacher

7 (8.6)

8 (10.5)

0.79

Public servant

3 (3.7)

2 (2.6)

> 0.99

Manufacturing worker

1 (1.2)

2 (2.6)

0.61

Agriculture

2 (2.5)

0 (0)

0.50

Business/store owner

1 (1.2)

2 (2.6)

0.61

Service provider

12 (14.8)

5 (6.6)

0.13

Housewife

20 (24.7)

23 (30.3)

0.48

Declined or unknown

2 (2.5)

0 (0)

0.50

Paternal characteristics

Age at delivery, median (IQR), y

38.0 (34.5–41.0)

37.0 (33.0–40.0)

0.55

Educational level (%)

High school dropout

0 (0)

0 (0)

> 0.99

High school graduate or vocational school graduate

30 (37.0)

25 (32.9)

0.62

College dropout

1 (1.2)

3 (3.9)

0.36

College graduate

42 (51.9)

39 (51.3)

> 0.99

Graduate school degree holder

6 (7.4)

9 (11.8)

0.42

Declined or unknown

2 (2.5)

0 (0)

0.50

Profession (%)

Healthcare worker

9 (11.1)

4 (5.3)

0.25

Office worker

31 (38.3)

32 (42.1)

0.63

Teacher

1 (1.2)

7 (9.2)

0.03

Public servant

9 (11.1)

3 (3.9)

0.13

Manufacturing worker

9 (11.1)

9 (11.8)

> 0.99

Agriculture

0 (0)

1 (1.2)

0.48

Business/store owner

10 (12.3)

7 (9.2)

0.61

Service provider

10 (12.3)

9 (11.8)

> 0.99

Househusband

0 (0)

2 (2.6)

0.23

Declined or unknown

2 (2.5)

2 (2.6)

> 0.99

Family income (%)

<3 million yen/year

1 (1.2)

1 (1.3)

> 0.99

3 million yen/year≤, < 5 million yen/year

7 (8.6)

11 (14.5)

0.32

5 million yen/year≤, < 7 million yen/year

24 (29.6)

17 (22.4)

0.36

7 million yen/year≤, < 10 million yen/year

30 (37.0)

25 (32.9)

0.62

10 million yen/year≤

16 (19.8)

22 (28.9)

0.20

Declined or unknown

3 (3.7)

0 (0)

0.25

Children characteristics

Obstetrical complications (%)

GDM

3 (3.7)

2 (2.6)

> 0.99

HDP

3 (3.7)

4 (5.3)

0.71

Placenta previa

3 (3.7)

1 (1.3)

0.62

Vaginal delivery

48 (59.3)

45 (58.4)

0.92

Gestational age at birth, median (IQR)

39.0 (38.0–40.0)

39.0 (37.0–40.0)

0.79

Preterm ≤ 36 weeks (%)

2 (3.7)

5 (6.5)

 

Full-term 37–41 weeks (%)

79 (97.5)

72 (93.5)

 

Post-term ≥ 42 weeks (%)

0 (0)

0 (0)

 

Birth weight, median (IQR)

3120.0 (2928.0-3418.0)

3045.0 (2776.0-3324.0)

0.19

<2,500 g (%)

5 (6.2)

12 (15.6)

 

2,501–2,999 g (%)

26 (32.1)

22 (28.6)

 

3,000–3,499 g (%)

37 (45.7)

31 (40.3)

 

3,500–3,999 g (%)

10 (12.3)

11 (14.3)

 

≥4,000 g (%)

3 (3.7)

1 (1.3)

 

Sex (%)

   

Female

42 (51.9)

38 (49.4)

0.87

Male

39 (48.1)

39 (50.6)

Number of the offspring (%)

Singleton

81 (100.0)

75 (98.7)

0.48

Twin

0 (0)

1 (1.3)

Sibling composition (%)

Yes

47 (58.0)

41 (53.2)

0.43

No

32 (39.5)

36 (46.8)

Declined or unknown

2 (2.5)

0 (0)

Use of group childcare services (e.g., preschools or daycare)

Yes

69 (85.2)

60 (77.9)

0.12

No

10 (12.3)

17 (22.1)

Declined or unknown

2 (2.5)

0 (0)

  1. IQR interquartile range, ICSI intracytoplasmic sperm injection, AOA artificial oocyte activation, y years, GDM gestational diabetes mellitus, HDP hypertensive disorders of pregnancy.