Table 1 Lectins and their known specificities.
Lectin/agglutinin | Specificity |
|---|---|
GNA (Galanthus nivalis) | α1–3 and α1–6 linked mannose of high mannose or hybrid glycan structures |
SNA (Sambucus nigra) | Neu5Acα2-6Gal, Neu5Acα2-6GalNAc |
MAA (Maackia amurensis) | Neu5Acα2-3Galβ1-4GlcNAc |
DSA (Datura stramonium) | Galβ1-4GlcNAc (N-acetyllactosamine) and their oligomers |
PNA (Peanut agglutinin) | Galβ1-3GalNAc (O-linked glycans) |
WGA (Wheat germ agglutinin) | GlcNAcβ1-4GlcNAc, Neu5Ac (Sialic acid) |
Con A (Concanavalin A) | α-D- mannose and α-D-glucose residues, branched α-mannosidic structures (high α-mannose types, hybrid and biantennary complex types of N-glycans) |
JAC (Jacalin) | (Neu5Ac) Galβ1-3GalNAc, Galβ1-3GalNAc (O-linked glycans) |