Fig. 4

The comparison of the human and dog gene-eigenvectors at the fourth and fifth levels. (A) Significant myelination-related gene subsets enriched at the poles of the human fourth polarized gene-eigenvector. According to their biological relevance, the enriched gene subsets are grouped from top to bottom by myelination, myelin-forming cell, myelin lipid metabolism, cholesterol metabolism, and fatty acid metabolism, shown in different colors. (B) Significant myelination-related gene subsets enriched at the poles of the dog fourth polarized gene-eigenvector. The grouping categories and colors are the same as in (A). (C) Significant cochlea development-related gene subsets enriched at the poles of the human fourth polarized gene-eigenvector. (D) Significant cochlea development-related gene subsets enriched at the poles of the dog fourth polarized gene-eigenvector.