Fig. 8
From: Saltations of cis-regulatory modules in Canidae and Hominidae
(A) The cluster tree of humans, dogs, and chimpanzees based on protein sequences and the tree based on proximal regulatory sequences. The left is based on protein sequences and the divergence times are marked on the tree. The right is based on the PCCs (Pearson correlation coefficients) and Euclidean distances between the motif-eigenvectors at the fourth CREF module. This module corresponds to cognition phenotypes and is obtained from proximal regulatory sequences. The Euclidean distances are marked on the tree. (B) The line charts of PCCs between the top nine motif-eigenvectors of five dogs and chimpanzees versus those of humans. The fourth, fifth, and ninth PCCs between humans and five dogs are greater than those between humans and chimpanzees.
