Table 5 MMPBSA energy components for the metformin–3G33 complex.

From: PEGylated liposomal metformin overcomes pharmacokinetic barriers to trigger potent mitochondrial disruption and cell cycle arrest in hepatocellular carcinoma

Energies (Kcal/mol)

       

Frames

VDWAALS

EEL

EGB

ESURF

GGAS

GSOLV

Total

Average

 − 9

 − 343.22

327.86

 − 2.97

 − 352.22

324.89

 − 27.33

SD

3.5

28.32

21.45

0.12

27.42

21.49

8.47

SEM

1.11

8.96

6.78

0.04

8.67

6.79

2.68

Back to article page