Table 2 List of the 25 metabolites, determined through the Mann-Whitney U test, whose concentration was significantly modified in breast cancers compared to healthy controls, after Benjamini-Hochberg correction.
Metabolite | Fold change | log2FC | P-Value | P-Value corrected |
|---|---|---|---|---|
Met | 0.75 | -0.42 | 3.55e-08 | 1.40e-05 |
Met-SO/Met | 1.68 | 0.75 | 2.67e-07 | 5.28e-05 |
Serotonin | 0.28 | -1.86 | 5.46e-07 | 7.19e-05 |
Lys | 0.79 | -0.34 | 1.14e-06 | 1.12e-04 |
Trp | 0.81 | -0.31 | 1.98e-06 | 1.56e-04 |
GABA | 0.69 | -0.54 | 2.46e-06 | 1.62e-04 |
Leu | 0.78 | -0.36 | 3.70e-06 | 2.09e-04 |
Thr | 0.76 | -0.39 | 5.31e-06 | 2.62e-04 |
3-Met-His | 0.47 | -1.08 | 1.10e-05 | 4.81e-04 |
Val | 0.81 | -0.30 | 1.40e-05 | 5.55e-04 |
PC aa C34:4 | 0.73 | -0.46 | 2.92e-05 | 1.05e-03 |
PC ae C34:3 | 0.79 | -0.34 | 5.24e-05 | 1.73e-03 |
PC ae C40:1 | 0.81 | -0.31 | 8.11e-05 | 2.32e-03 |
HArg | 0.70 | -0.51 | 8.67e-05 | 2.32e-03 |
PC aa C32:3 | 0.80 | -0.33 | 8.80e-05 | 2.32e-03 |
AABA | 0.76 | -0.40 | 6.44e-04 | 1.59e-02 |
Xanthine | 0.49 | -1.04 | 8.26e-04 | 1.92e-02 |
His | 0.86 | -0.22 | 9.19e-04 | 1.98e-02 |
PC ae C36:5 | 0.83 | -0.28 | 9.60e-04 | 1.98e-02 |
Asn | 0.84 | -0.26 | 1.00e-03 | 1.98e-02 |
GCA | 11.98 | 3.58 | 1.27e-03 | 2.38e-02 |
PC aa C28:1 | 0.86 | -0.22 | 1.59e-03 | 2.85e-02 |
Cer(d16:1/24:0) | 0.74 | -0.43 | 2.20e-03 | 3.78e-02 |
Tyr | 0.87 | -0.20 | 2.36e-03 | 3.89e-02 |
HexCer(d18:1/16:0) | 1.18 | 0.23 | 2.61e-03 | 4.12e-02 |
