Fig. 10 | Scientific Reports

Fig. 10

From: Integrated single-cell and transcriptomic analysis of bone marrow-derived metastatic neuroblastoma reveals molecular mechanisms of metabolic reprogramming

Fig. 10

MRPL21 knockdown inhibited cell viability, migration, and invasion in neuroblastoma cells. RT-qPCR (A) and Western blot (B) analyses confirmed the successful knockdown of MRPL21 by siRNA in SH-SY5Y and SK-N-BE2 cells. NC indicates the negative control group. The effects of MRPL21 knockdown on cell viability, migration, and invasion were evaluated using CCK-8 (C, D), wound healing (E, F), and transwell invasion (G) assays, respectively. Data are presented as mean ± standard deviation (SD). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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