Fig. 4

Effects of avocado peel and seed extracts on pro-inflammatory cytokines in UVB-irradiated BJ cells. The cells were pre-treated with 12.5–50 µg/ml of the extracts, irradiated with 40 mJ/cm2 UVB, maintained in the culture medium for 24 h, and collected supernatant for determining the levels of TNF-α, IL-1β, and IL-6 by ELISA. The statistical significance of differences was evaluated by one-way ANOVA followed by Tukey’s test. **p < 0.01 compared to the non-irradiated control; ##p < 0.01 compared to the UVB-irradiated control.