Table 2 Logistic regression analyses on AKI for changes in preoperative serum creatinine.

From: Normalization of elevated preoperative serum creatinine and acute kidney injury after cardiac surgery: a retrospective cohort study

 

AKI

Severe AKI

Persistent AKI

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Unadjusted

 Stable sCr Group

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 

 Normalized sCr Group

3.39 (1.85–6.23)

< 0.001

4.50 (2.07–9.78)

< 0.001

3.79 (1.97–7.27)

< 0.001

 Worsened sCr Group

10.35 (5.25–20.41)

< 0.001

6.57 (3.39–12.74)

< 0.001

8.60 (4.88–15.17)

< 0.001

Adjusted*

 Stable sCr Group

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 

 Normalized sCr Group

2.51 (1.30–4.85)

0.006

3.40 (1.37–8.45)

0.008

2.87 (1.36–6.05)

0.006

 Worsened sCr Group

7.79 (3.77–16.11)

< 0.001

5.38 (2.46–11.78)

< 0.001

7.90 (4.10‒15.25)

< 0.001

  1. AKI acute kidney injury, sCr serum creatinine.
  2. *Multivariable logistic regression was adjusted for age, gender, hypertension, diabetes mellitus, NYHA class III/IV, ACEIs or ARBs, diuretics, statins, NSAIDs, contrast agent, baseline eGFR, type of surgery, surgery time, cardiopulmonary bypass, and intraoperative blood transfusion volume.