Fig. 3 | Scientific Reports

Fig. 3

From: An effective approach to cartilage regeneration using antler stem cell-conditioned medium

Fig. 3

Effects of the ASC-CM on the proliferation and migration. (A) Optimization of the ratio of ASC-CM to medium using rat-chondrocytes, ****P < 0.0001. (B,C). Effects of ASC-CM (1:16) on the proliferation of rat-chondrocytes and rat-BMSCs, n = 3, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. (D,E) Effects of the ASC-CM on proliferation of rat-chondrocytes and rat-BMSCs by Edu, Scale bar = 400 μm. (F,G) Percentages of Edu-positive cells in rat-chondrocytes and rat-BMSCs, n = 3, *P < 0.05, ****P < 0.0001. (H) Quantitative analysis of the migrated rat-BMSCs, *P < 0.05, **P < 0.01. (I) Migration assay of rat-BMSCs, Scale bar = 1000 μm.

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