Fig. 1 | Scientific Reports

Fig. 1

From: Interaction between serum levels of Porphyromonas gingivalis immunoglobulin G and lutein/zeaxanthin is associated with risk for age-related macular degeneration

Fig. 1

The Porphyromonas gingivalis-related AMD risk significantly (P for interaction < 0.0001) varies by serum levels of lutein/zeaxanthin (≥ 0.35 µmol/L vs. <0.35 µmol/L). The four P. gingivalis IgG groups are ≤ 57 EU (category 1), 58–65 EU (category 2), 66–119 EU (category 3) and > 119 EU (category 4). The ORs (95% CIs; P value) for the four P. gingivalis IgG groups (from high to low) in the low serum lutein/zeaxanthin category are 1 (referent), 0.80 (0.45 to 1.42; P = 0.44), 0.65 (0.40 to 1.07; P = 0.09), and 0.43 (0.28 to 0.66; P = 0.0001), and they are 0.74 (0.48 to 1.15; P = 0.18), 0.54 (0.37 to 0.80; P = 0.002), 0.42 (0.28 to 0.63; P < 0.0001), and 0.43 (0.28 to 0.65; P < 0.0001) in the high serum lutein/zeaxanthin category, respectively. OR, odds ratio; CI, confidence interval; IgG, immunoglobulin G; EU, enzyme-linked immunosorbent assay unit.

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