Table 4 Logistic analysis relating serum Porphyromonas gingivalis Immunoglobulin G levels to risk for age-related macular degeneration.

From: Interaction between serum levels of Porphyromonas gingivalis immunoglobulin G and lutein/zeaxanthin is associated with risk for age-related macular degeneration

Serum P. gingivalis IgG level (EU)

Adjusted OR (95% CI)a

Model 1

Model 2

Model 3

Model 4

Model 5

≤ 57 (referent)

1

1

1

1

1

58–65

1.19 (1.05 to 1.35)

1.23 (1.07 to 1.41)

1.24 (1.07 to 1.43)

1.27 (1.16 to 1.38)

1.28 (1.17 to 1.40)

66–118

1.44 (1.31 to 1.58)

1.48 (1.27 to 1.73)

1.51 (1.32 to 1.73)

1.55 (1.42 to 1.68)

1.58 (1.46 to 1.72)

> 119

2.02 (1.66 to 2.46)

2.07 (1.67 to 2.55)

2.03 (1.52 to 2.72)

2.12 (1.68 to 2.66)

2.04 (1.62 to 2.58)

 

P for trend = 0.04

P for trend = 0.05

P for trend = 0.06

P for trend = 0.06

P for trend = 0.09

  1. a Model 1: adjusted for age; Model 2: Model 1 additionally adjusted for sex, race, BMI and education; Model 3: Model 2 additionally adjusted for smoking history and alcohol intake; Model 4: Model 3 additionally adjusted for serum vitamin C, E, lutein/xeaxanthin, and CRP levels; Model 5: Model 4 additionally adjusted for two clinical periodontal measurements, mBOP and mCAL.
  2. OR, odds ratio; CI, confidence interval; CRP, C reactive protein; IgG, immunoglobulin G; EU, enzyme-linked immunosorbent assay unit; mBOP, mean number of tooth sites that bled on probing; mCAL, mean clinical attachment loss.
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