Table 3 Percentage of patients presenting at least one event according to the capping percentage.

Patient with at least one toxicity

7 (53.8)

34 (80.9)

36 (72)

16 (69.5)

Hematological toxicities Grade ≥ at 3

 Agranulocytosis

5 (3.8)

0 (0)

3 (7.1)

2 (4)

0 (0)

p = 0.071

 Leucopenia

4 (3.1)

0 (0)

2 (4.7)

1 (2)

1 (4)

p = 0.56

 Neutropenia

21 (16.2)

2 (15.4)

9 (21.4)

7 (14)

3 (12)

P = 0.79

 Anemia

3 (2.3)

0 (0)

0 (0)

2 (4)

1 (4)

p = 0.33

 Febrile aplasia

7 (5.4)

2 (15.4)

1 (2.3)

3 (6)

1 (4)

p = 0.32

 Thrombopenia

3 (2.3)

0 (0)

0 (0)

2 (4)

1 (4)

P = 0.32

Non-hematological toxicities Grade ≥ at 2

 Asthenia

34 (26.2)

2 (15.4)

10 (23.8)

14 (28)

8 (32)

p = 0.50

 Stomatitis

11 (8.5)

2 (15.4)

4 (9.5)

3 (6)

2 (8)

p = 0.73

 Nausea

34 (26.2)

6 (46.1)

12 (28.5)

11 (22)

5 (20)

P = 0.28

 Nail toxicity

4 (3.1)

1 (7.7)

3 (7.1)

0 (0)

0 (0)

p = 0.98

 Skin toxicity

7 (5.4)

0 (0)

4 (9.5)

3 (6)

0 (0)

p = 0.31

 Paresthesia

4 (3.1)

0 (0)

1 (2.3)

3 (6)

0 (0)

p = 0.44

 Neuropathy

10 (7.7)

0 (0)

5 (11.9)

3 (6)

2 (8)

p = 0.56

 Alopecia

2 (1.5)

0 (0)

0 (0)

2 (4)

0 (0)

p = 0.002

 Hand-foot syndrome

9 (6.9)

0 (0)

4 (9.5)

2 (4)

3 (12)

p = 0.44

 Cephalalgia

1 (0.8)

0 (0)

0 (0)

1 (2)

0 (0)

p = 1

 Anorexia

2 (1.5)

0 (0)

0 (0)

1 (2)

1 (4)

p = 0.36

 Hot flash

1 (0.8)

0 (0)

1 (2.3)

0 (0)

0 (0)

p = 1

 Vomiting

2 (1.5)

0 (0)

1 (2.3)

0 (0)

1 (4)

p = 0.36

 Constipation

1 (0.8)

0 (0)

1 (2.3)

0 (0)

0 (0)

p = 1

 Pain

1 (0.5)

0 (0)

0 (0)

0 (0)

1 (4)

p = 1

 Diarrhea

13 (10)

1 (7.7)

6 (14.2)

5 (10)

1 (4)

p = 0.69

Chemotherapy dose cancellation

7 (5.4)

0 (0)

2 (4.7)

5 (10)

0 (0)

0.18

Chemotherapy dose reduction

35 (26.9)

0 (0)

17 (40.4)

10 (20)

8 (32)

p = 0.017

Chemotherapy delay

4 (3.1)

0 (0)

2 (4.7)

1 (2)

1 (4)

p = 0.64

Hospitalization

18 (13.8)

3 (23.1)

4 (9.5)

8 (16)

3 (12)

p = 0.39