Table 4 Univariate and multivariable logistic regression regarding toxicity occurrence and the percentage of capping.

From: Influence of capping chemotherapy prescriptions on efficacy and tolerability in medium and high-risk early-stage breast cancer

Variable

Univariate

Multivariable

Capping groups

OR (95% CI)

p

 

Adjusted OR (95% CI)

p

All toxicities

Reference group [90–100]

 

Reference group [90–100]

  

[0–10[

0.92 (0.24–3.52)

0.899

[0–10[

0.92 (0.23–3.72)

0.909

[10–50[

3.34 (1.11–10.06)

0.032

[10–50[

2.15 (0.67–6.91)

0.197

[50–90[

1.67 (0.62–4.49)

0.309

[50–90[

1.34 (0.48–3.78)

0.576

Hematologic toxicities

Ref=[90–100]

     

[0–10[

0.95 (0.15–6.06)

0.961

   

[10–50[

2.1 (0.59–7.41)

0.249

   

[50–90[

1.48 (0.42–5.42)

0.542

   

Non-hematologic toxicities

Ref=[90–100]

     

[0–10[

1.48 (0,39-5.71)

0.565

   

[10–50[

3.59 (1.26–10.22)

0.017

   

[50–90[

1.62 (0.62–4.26)

0.328

   
  1. All toxicities represent the hematological toxicities grade ≥ 3 and the non-hematological toxicities grade ≥ 2 according to the CTCAE v5.0 criteria. Hematological toxicities were defined as a grade ≥ 3 and the non-hematological toxicities were defined as a grade ≥ 2 OR: odds ratio.
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