Table 2 Physicochemical and drug-like characteristics of chosen compounds evaluated using SwissADME.

From: Citronellol silver nanoconjugates as a therapeutic strategy for glioblastoma through computational and experimental evaluation

Physiochemical properties

Compounds name

Mol. Weight

H-Bond acceptors

H-Bond Donor

Rotatable Bonds

LogP (≤ 5)

Polar surface area

Molar refreactivity

(≤ 500 da)

(≤ 10)

(≤ 5)

< 140 Å2

Citronellol

156.27

1

1

5

3.43

20.23

50.87

CN@AgNPs

263.13

1

0

6

3.92

9.23

49.74

Temozolomide

194.15

5

1

1

-0.54

108

44.40

Drug likeness

Compounds

Lipinski

Ghoose

Veber

Egan

Bioavailability score

Violations

Citronellol

Yes

No

Yes

Yes

0.55

1

CN@AgNPs

Yes

Yes

Yes

Yes

0.55

0

Temozolomide

Yes

No

Yes

Yes

0.55

1

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