Table 3 The absorption, distribution, excretion, metabolism, and toxicity of citronellol and CN@AgNPs using ADMETlab tool.
Pharmacokinetic parameters | ||||||||
|---|---|---|---|---|---|---|---|---|
Compounds Name | Caco-2 permeability | Gastrointestinal absorption | P-Glycoprotein Substrate | Plasma Protein binding substrate | Blood Brain Barrier | Half Life | Cytochrome P450 inhibitor | Toxicophore alert |
Citronellol | -4.315 | High | No | 85.63% | Y | 0.61 | No | 0 |
CN@AgNPs | -4.362 | High | No | 88.56% | Y | 0.21 | No | 0 |
Temozolomide | -5.155 | High | No | 11.5% | N | 1.95 | No | 0 |
