Fig. 7 | Scientific Reports

Fig. 7

From: Potential of tadalafil and tadalafil-cellulose nanocomposite in preventing postsurgical abdominal adhesions in a rat cecal abrasion model

Fig. 7

Histopathological examination of intestine and adhesion tissue by H&E staining. The adhesion group displayed (A, B) an adhesion site between intestines (star), and (C, D, E) infiltration of neutrophils (star), infiltration between mucosal intestinal glands with mononuclear inflammatory cells and giant cells (arrows). The tadalafil-treated group showed (F, G, H) no adhesion, and (I, J) hyperemia of blood vessels (notched arrow) with mild mucosal inflammatory cell infiltration (arrow). The cellulose-treated group showed (K, L) an adhesion site between intestines (star), and (M, N, O) giant cells (arrows), mucosal inflammatory cellular infiltration (star). The tadalafil/cellulose-treated group displayed (P, Q) no adhesion, while (R) showed giant cells (notched arrow). The sham group (S) showed no adhesion and (T) normal intestinal mucosa. The scale bars in panels (A, B, G, K, L, P, and Q) = 200 μm, panels (F, H, M, and S) = 100 μm, (C, D, E, I, J, N, O, R, and T) = 20 μm.

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