Fig. 5

The distinctive expression patterns of samples expressing high levels of CE1 in GSE167523. (A) A total of 727 genes exhibiting differential expression (DEGs) are identified. (B) The clustering heatmap of the DEGs displays the discernible expression patterns that differentiate these groups. In the color bar situated above the heatmap, the color blue denotes MASLD or men, while the color pink denotes MASH or women. (C) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enrichment analysis for the up-regulated genes. (D) Gene Ontology (GO) biological processes enrichment analysis for the down-regulated genes. Both enrichment analyses were performed in the clusterProfiler tool.