Fig. 3
From: Efficacy and safety of a novel flow-disruptor device in a rabbit aneurysm model: a preliminary study
Novel flow disruptor (NFD) placement into rabbit elastase-induced aneurysm model and representative follow-up angiographic and respective histological images. (a ) Digital subtraction angiography (DSA) after NFD detachment showing immediate flow disruption and complete occlusion on follow-up. (b) Histology image showing loose connective tissue within the aneurysm cavity and neointima layers across the neck level. (c) DSA after NFD detachment showing moderate flow disruption and near complete occlusion on follow-up. (d) Histology image revealing concave connective tissue across the aneurysm neck, with partial thrombus and a neck remnant observed on follow-up angiography in the (c). (e) DSA after NFD detachment showing mild flow disruption and incomplete occlusion on follow-up. (f) Histology image showing minimal connective tissue in the aneurysm cavity, with no neointimal layer at the neck.
