Fig. 4 | Scientific Reports

Fig. 4

From: Functional roles of purified yapsins from Candida glabrata (Nakaseomyces glabratus) in immune modulation and cross-species biofilm formation

Fig. 4

Comparison of amino acid sequence fragments of C. glabrata Yps3 (accession number Q6FVI0), C. glabrata Yps9 (accession number Q6FVH5), and C. albicans Sap7 (accession number P43096), aligned using Clustal Omega. The amino acid residues Met242 and Thr467 in the Sap7 sequence, suspected to restrict access to the binding site and contribute to the enzyme insensitivity to pepA inhibition, are highlighted, along with the corresponding residues in Yps3 and Yps9. For a full sequence alignment, see Fig. S3 in the Supplementary materials.

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