Table 2 Gene clusters associated with secondary metabolites production identified in P. polymyxa K16 using antismash. Nucleotide positions within the genome are reported. Abbreviation used: NRPS, Non-ribosomal peptide synthetase; T3PKS, type III polyketide synthase; T1PKS, type I polyketide synthase.
n° | Gene cluster | From (nt) | To (nt) | Most similar known cluster | Similarity |
---|---|---|---|---|---|
1 | PRE-containing | 486,310 | 505,872 | ||
2 | NRPS | 7551,076 | 813,652 | Fusaricidin B | 100% |
3 | Phosphonate | 999,609 | 1,031,728 | ||
4 | NRPS | 1,655,609 | 1,728,892 | Polymyxin B | 100% |
5 | T3PKS, transAT-PKS, NRPS | 3,073,104 | 3,173,353 | Aurantinin B/C/D | 35% |
6 | Cyclin-lactone-autoinducer | 3,691,073 | 3,711,294 | ||
7 | T1PKS, NRPS | 3,898,768 | 3,992,603 | Gramicidin S | 6% |
8 | NRPS | 4,229,946 | 4,322,819 | tridecaptin | 100% |
9 | Cyclic-lactone-autoinducer | 4,659,425 | 4,680,068 | ||
10 | NRPS-like | 4,686,536 | 4,729,778 | ||
11 | Lenthipeptide-class-i | 5,041,741 | 5,068,747 | paenilan | 100% |
12 | lassopeptide | 5,397,383 | 5,421,498 | paeninodin | 40% |
13 | NRPS, transAT-PKS | 5,456,675 | 5,556,654 | ||
14 | proteusin | 5,607,403 | 5,627,639 | ||
15 | NI-independent-siderophore | 5,794,941 | 5,812,342 |