Table 1 Antimicrobial activities of ZnO2 NPs and doped ZnO2 NPs (with and without ligand capping) against MRSA (a) and BC (b). All experiments were performed in triplicates (N = 3), while the concentrations were presented as (μg/ml)

From: Ligand-controlled growth and stabilization of doped ZnO2 nanoparticles for dual antibacterial and enzyme inhibition

Compounds

Zone of inhibition (mm) for Methicillin-resistant Staphylococcus aureus, concentration = µg/ml, N = 3 (triplicates)

250 µg/ml

500 µg/ml

750 µg/ml

1000 µg/ml

(a)

ZnO2-NPs

6.1 ± 1.5

6.2 ± 1.7

7.2 ± 1.6

7.7 ± 0.9 (MIC)

3% Mn-doped ZnO2

6.2 ± 2.4 (MIC)

6.3 ± 2.1 (MBC)

7.6 ± 2.1

8.9 ± 1.7

5% Co-doped ZnO2 cit

9.2 ± 1.7

9.5 ± 1.5 (MIC/MBC)

12.2 ± 2.7

12.5 ± 2.0

3% Mn-doped ZnO2 dmlt

6.2 ± 2.6 (MIC/MBC)

6.5 ± 2.0

8.3 ± 2.6

10.3 ± 1.7

Negative control

0.0 ± 0

0.0 ± 0

0.0 ± 0

0.0 ± 0

Ciprofloxacin

13.3 ± 2.0

13.3 ± 2.6

15.4 ± 2.4

14.2 ± 3.0

Compounds

Zone of inhibition (mm) for Bacillus cereus (BC), concentration = µg/ml, N = 3 (triplicates)

250 µg/ml

500 µg/ml

750 µg/ml

1000 µg/ml

(b)

ZnO2-NPs

7.5 ± 2.0

7.9 ± 1.7

8.0 ± 2.1

8.6 ± 0.9 (MIC)

3% Mn-doped ZnO2

9.0 ± 1.6

10 ± 2.1 (MIC)

10 ± 2.6

11 ± 1.9

5% Co-doped ZnO2 cit

6.2 ± 1.7

6.3 ± 2.1 (MIC/MBC)

6.3 ± 1.5

6.4 ± 1.5

3% Mn-doped ZnO2 dmlt

6.2 ± 2.4 (MIC)

6.3 ± 2.2 (MBC)

11.4 ± 2.3

12.3 ± 1.9

Negative control

0.0 ± 0

0.0 ± 0

0.0 ± 0

0.0 ± 0

Ciprofloxacin

14.1 ± 2.5

15.5 ± 2.6

15.6 ± 2.6

17.5 ± 1.9