Table 3 The physicochemical properties of potent compounds with the SwissADME database.
Code | Physicochemical properties | Pharmacokinetics | Drug likeness | |||
|---|---|---|---|---|---|---|
Molecular weight (g/mol) | No. of H-bond acceptors | No. of H-bond donors | GI absorption | BBB permeation | Lipinski | |
6d | 382.22 | 5 | 0 | High | Yes | Yes; 0 violation |
6e | 355.76 | 6 | 0 | High | Yes | Yes; 0 violation |
6g | 372.21 | 5 | 0 | High | Yes | Yes; 0 violation |
6h | 395.42 | 6 | 0 | High | Yes | Yes; 0 violation |
6i | 348.32 | 7 | 0 | High | Yes | Yes; 0 violation |
6m | 387.32 | 9 | 0 | High | Yes | Yes; 0 violation |
