Fig. 1
From: Association of retinal layer thickness with brain volume and cortical thickness in older adults

Voxel-based morphometry analysis showing associations between RNFL thickness and regional brain volumes. Results are displayed at an uncorrected threshold of p < 0.001, with a cluster size threshold of 100 voxels applied to reduce the risk of false positives. Panel (a) shows results for outer RNFL thickness, with significant clusters located in the left superior frontal, right inferior parietal, and left inferior temporal cortices (from top to bottom). Panel (b) shows a significant cluster for total RNFL thickness in the right inferior parietal cortex. The color bar represents t-values. For each significant cluster, a scatter plot is presented to the right, showing the association between RNFL thickness (μm) and cluster mean gray matter volume, adjusted for age, sex, and total intracranial volume. Each plot displays unstandardized β coefficients, P-values, and R² values from multiple linear regression models.