Fig. 3

The proportion of enriched modules is consistently improved with squared weights for each of mult, min and log weighting schemes. Discounting min not squared, which produces at most 4 modules, min (squared) has the largest proportion gBPMs with both pathways enriched for some known function (blue plus orange bars). On the other hand, mult (squared) with \(c=90\) has the fewest proportion of gBPMs with neither module enriched for a known function (red bar): over 90% of the modules returned by this method have at least one component pathway functionally enriched.